node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HORMAD1 | MEI1 | ENSCAFP00000017772 | ENSCAFP00000001457 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Meiotic double-stranded break formation protein 1. | 0.815 |
HORMAD1 | RAE1 | ENSCAFP00000017772 | ENSCAFP00000017710 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | SPO11 initiator of meiotic double stranded breaks. | 0.958 |
HORMAD1 | REC114 | ENSCAFP00000017772 | ENSCAFP00000026260 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | REC114 meiotic recombination protein. | 0.735 |
HORMAD1 | REC8 | ENSCAFP00000017772 | ENSCAFP00000017702 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | REC8 meiotic recombination protein. | 0.874 |
HORMAD1 | STRA8 | ENSCAFP00000017772 | ENSCAFP00000004776 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Stimulated by retinoic acid 8. | 0.515 |
HORMAD1 | SYCE1 | ENSCAFP00000017772 | ENSCAFP00000033815 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex central element protein 1. | 0.874 |
HORMAD1 | SYCE2 | ENSCAFP00000017772 | ENSCAFP00000025181 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex central element protein 2. | 0.657 |
HORMAD1 | SYCE3 | ENSCAFP00000017772 | ENSCAFP00000041157 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex central element protein 3. | 0.828 |
HORMAD1 | SYCP1 | ENSCAFP00000017772 | ENSCAFP00000037843 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex protein 1. | 0.922 |
HORMAD1 | SYCP3 | ENSCAFP00000017772 | ENSCAFP00000038284 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. | 0.490 |
MEI1 | HORMAD1 | ENSCAFP00000001457 | ENSCAFP00000017772 | Meiotic double-stranded break formation protein 1. | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | 0.815 |
MEI1 | RAE1 | ENSCAFP00000001457 | ENSCAFP00000017710 | Meiotic double-stranded break formation protein 1. | SPO11 initiator of meiotic double stranded breaks. | 0.815 |
MEI1 | REC114 | ENSCAFP00000001457 | ENSCAFP00000026260 | Meiotic double-stranded break formation protein 1. | REC114 meiotic recombination protein. | 0.950 |
MEI1 | REC8 | ENSCAFP00000001457 | ENSCAFP00000017702 | Meiotic double-stranded break formation protein 1. | REC8 meiotic recombination protein. | 0.747 |
MEI1 | STRA8 | ENSCAFP00000001457 | ENSCAFP00000004776 | Meiotic double-stranded break formation protein 1. | Stimulated by retinoic acid 8. | 0.485 |
MEI1 | SYCE1 | ENSCAFP00000001457 | ENSCAFP00000033815 | Meiotic double-stranded break formation protein 1. | Synaptonemal complex central element protein 1. | 0.850 |
MEI1 | SYCE2 | ENSCAFP00000001457 | ENSCAFP00000025181 | Meiotic double-stranded break formation protein 1. | Synaptonemal complex central element protein 2. | 0.590 |
MEI1 | SYCE3 | ENSCAFP00000001457 | ENSCAFP00000041157 | Meiotic double-stranded break formation protein 1. | Synaptonemal complex central element protein 3. | 0.451 |
MEI1 | SYCP1 | ENSCAFP00000001457 | ENSCAFP00000037843 | Meiotic double-stranded break formation protein 1. | Synaptonemal complex protein 1. | 0.785 |
MEI1 | SYCP3 | ENSCAFP00000001457 | ENSCAFP00000038284 | Meiotic double-stranded break formation protein 1. | N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. | 0.412 |