STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRBNCereblon. (444 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 
 0.999
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 
 0.980
CNTF
Uncharacterized protein.
    
 
 0.976
IKZF1
IKAROS family zinc finger 1.
    
 
 0.972
BRD4
Bromodomain containing 4.
    
 
 0.886
IKZF3
IKAROS family zinc finger 3.
    
 
 0.882
RBX1
Ring-box 1.
    
 
 0.876
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 
 0.875
CSNK1A1
Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily.
   
 
 0.827
ZNF692
Zinc finger protein 692.
    
 
 0.764
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.