STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC1Tetratricopeptide repeat domain 1. (293 aa)    
Predicted Functional Partners:
NEDD8
NEDD8 ubiquitin like modifier.
   
 
 0.545
RNF41
Ring finger protein 41.
   
   0.531
CPNE1
RNA binding motif protein 12.
   
  
 0.526
VWA3B
Von Willebrand factor A domain containing 3B.
      
 0.501
HSPA4
Heat shock 70 kDa protein 4.
    
 
 0.489
VPS13D
Vacuolar protein sorting 13 homolog D.
      
 0.482
LOC477430
Uncharacterized protein.
   
    0.476
PPP1R7
Protein phosphatase 1 regulatory subunit 7.
   
    0.476
PRDM11
PR/SET domain 11.
   
  
 0.446
KLHL14
Kelch like family member 14.
      
 0.443
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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