STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOVA1NOVA alternative splicing regulator 1. (507 aa)    
Predicted Functional Partners:
PRSS53
Serine protease 53; Belongs to the peptidase S1 family.
      
 0.806
DCC
DCC netrin 1 receptor.
   
  
 0.608
NTN1
Netrin 1.
      
 0.586
LIN7C
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
   
  
 0.584
EIF1AD
Eukaryotic translation initiation factor 1A domain containing.
   
  
 0.565
PTBP2
Polypyrimidine tract binding protein 2.
   
 
 0.549
ROBO2
Roundabout guidance receptor 2.
   
  
 0.543
CACNB4
Calcium voltage-gated channel auxiliary subunit beta 4.
   
  
 0.537
SRRM4
Serine/arginine repetitive matrix 4.
   
  
 0.523
TREM2
Triggering receptor expressed on myeloid cells 2.
   
  
 0.510
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.