STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1388 aa)    
Predicted Functional Partners:
IL-15L
Uncharacterized protein.
      
 0.564
PIK3R3
Uncharacterized protein.
   
 
 0.563
LGI4
Leucine rich repeat LGI family member 4.
      
 0.553
SUPT5H
Transcription elongation factor SPT5.
   
 
 0.504
ARHGEF1
DH domain-containing protein.
   
0.493
ANKRD23
Ankyrin repeat domain 39.
   
 
 0.490
CDC42
Cell division cycle 42.
    
 0.486
PLCE1
Phosphoinositide phospholipase C.
      
 0.482
ANKRD2
Ankyrin repeat domain 2.
   
 
 0.445
SPHK1
Sphingosine kinase 1.
      
 0.439
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.