STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGPP1Sphingosine-1-phosphate phosphatase 1. (445 aa)    
Predicted Functional Partners:
SGPL1
Sphingosine-1-phosphate lyase 1.
    
 0.979
SPHK2
Sphingosine kinase 2.
  
 0.976
SPHK1
Sphingosine kinase 1.
  
 0.959
CERS6
Ceramide synthase 6.
    
 0.943
CERS4
Ceramide synthase 4.
    
 0.940
SMPD2
Sphingomyelin phosphodiesterase 2.
    
 0.938
UGCG
UDP-glucose ceramide glucosyltransferase.
    
 0.937
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
 
 0.936
SMPD4
Sphingomyelin phosphodiesterase 4.
   
 
 0.936
ACER2
Alkaline ceramidase 2.
     
 0.936
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.