STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)    
Predicted Functional Partners:
LAMTOR1
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.
   
 0.999
LAMTOR2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
   
 0.999
SLC38A9
Solute carrier family 38 member 9.
    
 0.998
RRAGC
Ras related GTP binding C.
    
 0.996
RRAGD
Ras related GTP binding D.
    
 0.994
LAMTOR5
Uncharacterized protein.
   
 0.991
RRAGA
Ras related GTP binding A.
    
 0.982
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.976
LAMTOR4
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.
    
 0.968
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (By similarity).
    
 0.937
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.