STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK5Polo like kinase 5. (336 aa)    
Predicted Functional Partners:
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.823
FZR1
Fizzy and cell division cycle 20 related 1.
   
 
 0.735
PLK4
Polo like kinase 4.
   
 
 0.725
PPP4C
Serine/threonine-protein phosphatase.
   
 
 0.698
RAD21
RAD21 cohesin complex component.
   
 
 0.677
RAD21L1
RAD21 cohesin complex component like 1.
   
 
 0.677
AURKC
Aurora kinase C; Belongs to the protein kinase superfamily.
   
 
 0.669
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 
 0.651
SMC3
Structural maintenance of chromosomes protein.
   
 
 0.651
CDC20B
Cell division cycle 20B.
   
 
 0.644
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.