STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000038290annotation not available (97 aa)    
Predicted Functional Partners:
LOC100687983
Uncharacterized protein.
   
 
 0.800
J9P1X3_CANLF
Uncharacterized protein.
   
 
 0.800
ANXA2
Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9; Belongs to the annexin family.
   
 
 0.800
ENSCAFP00000050541
Uncharacterized protein.
   
 
 0.800
ANXA1
Annexin.
   
 
 0.706
AHNAK
AHNAK nucleoprotein.
   
 
 0.658
AHNAK-2
PDZ domain-containing protein.
   
 
 0.658
HLTF
Helicase like transcription factor.
   
 
 0.586
S100A6
S100 calcium binding protein A8; Belongs to the S-100 family.
   
 
 0.561
ENSCAFP00000060641
EF-hand domain-containing protein.
   
 
0.561
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.