STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP23Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family. (241 aa)    
Predicted Functional Partners:
TRMT5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
   
  
 0.876
CHCHD4
Coiled-coil-helix-coiled-coil-helix domain containing 4.
   
 
 0.755
MSRB3
Methionine sulfoxide reductase B3.
   
  
 0.643
MFSD6
Major facilitator superfamily domain containing 6.
      
 0.570
SAMD11
Sterile alpha motif domain containing 11.
      
 0.570
IGFBP2
Insulin like growth factor binding protein 2.
   
  
 0.567
HCCS
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
    
 
 0.558
PRCD
Photoreceptor disk component PRCD; Involved in vision.
      
 0.548
TIMM10
Translocase of inner mitochondrial membrane 10.
   
 
 0.547
MIPEP
Mitochondrial intermediate peptidase.
   
  
 0.532
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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