STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXN2Forkhead box N2. (439 aa)    
Predicted Functional Partners:
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2.
    
 
 0.692
POLR3A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.663
TNFSF12
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
   
  
 0.640
TTYH2
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.559
SOX15
SRY-box 15.
   
 
 0.559
VDR
Vitamin D receptor.
    
 
 0.505
PPP1R21
Protein phosphatase 1 regulatory subunit 21.
      
 0.502
AKIRIN2
Akirin 2.
    
 
 0.490
KANSL1L
KAT8 regulatory NSL complex subunit 1 like.
    
 
 0.490
DNAAF5
Dynein axonemal assembly factor 5.
      
 0.481
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.