STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCXDoublecortin. (403 aa)    
Predicted Functional Partners:
PNCK
Pregnancy up-regulated nonubiquitous CaM kinase.
 
 
 
 0.908
PSKH2
Protein serine kinase H2; Belongs to the protein kinase superfamily.
 
 
 
 0.902
NES
Nestin; Belongs to the intermediate filament family.
   
  
 0.863
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
    
 
 0.852
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
 
      0.826
PHKG2
Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily.
 
 
    0.823
PSKH1
Protein serine kinase H1; Belongs to the protein kinase superfamily.
 
  
 
 0.800
CAMK1
Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily.
 
  
 
 0.781
CAMK1D
Calcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily.
 
 
 
 0.763
MKNK1
MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily.
 
      0.755
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.