STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)    
Predicted Functional Partners:
CIDEA
Cell death inducing DFFA like effector a.
   
  
 0.785
PRDM16
PR/SET domain 16.
   
  
 0.782
PKIB
cAMP-dependent protein kinase inhibitor beta; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.715
PLIN1
Perilipin; Belongs to the perilipin family.
    
 
 0.681
DIO2
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.679
FABP6
Fatty acid binding protein 6.
   
  
 0.674
MOGAT2
Monoacylglycerol O-acyltransferase 2.
   
  
 0.650
TMEM26
Transmembrane protein 26.
      
 0.625
PPARGC1A
PPARG coactivator 1 alpha.
    
 
 0.603
PLIN2
Perilipin; Belongs to the perilipin family.
    
 
 0.592
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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