STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YAP1Yes associated protein 1. (325 aa)    
Predicted Functional Partners:
LATS2
Non-specific serine/threonine protein kinase.
   
 0.993
LATS1
Large tumor suppressor kinase 1.
   
 0.992
TEAD2
TEA domain transcription factor 2.
   
 0.987
TEAD1
TEA domain transcription factor 1.
   
 0.985
TEAD4
Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
   
 0.985
AMOT
Angiomotin.
    
 0.981
TEAD3
TEA domain transcription factor 3.
   
 0.981
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
   
 0.955
SMAD3
Mothers against decapentaplegic homolog.
   
 0.944
FBXW11
F-box and WD repeat domain containing 11.
   
 0.942
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.