STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEZ6L2Seizure related 6 homolog like 2. (916 aa)    
Predicted Functional Partners:
ASPHD1
Aspartate beta-hydroxylase domain containing 1.
 
 
  
 0.808
TMEM25
Transmembrane protein 25.
   
  
 0.681
ANKRD13B
Ankyrin repeat domain 13B.
    
 
 0.675
FRMPD4
FERM and PDZ domain containing 4.
   
  
 0.673
CACHD1
Cache domain containing 1.
   
  
 0.641
NETO2
Neuropilin and tolloid like 2.
      
 0.639
TUBGCP4
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
    
 
 0.601
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
   
 
 0.600
EML1
EMAP like 1.
    
 
 0.576
INO80E
INO80 complex subunit E.
    
 
 0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.