TUT7 protein (Canis lupus familiaris) - STRING interaction network

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Score

TUT7

Terminal uridylyl transferase 7. (1542 aa)

Predicted Functional Partners:

DIS3L2

0.858

LIN28A

0.685

PABPC1

0.657

TENT4B

0.601

DIS3

0.592

XRN1

0.582

LIN28B

0.546

PNLDC1

0.544

TDRKH

0.516

AGO2

0.512

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	PABPC1	ENSCAFP00000043303	ENSCAFP00000039955	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.490
AGO2	TUT7	ENSCAFP00000043303	ENSCAFP00000038915	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Terminal uridylyl transferase 7.	0.512
AGO2	XRN1	ENSCAFP00000043303	ENSCAFP00000051235	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	5'-3' exoribonuclease 1.	0.537
DIS3	TENT4B	ENSCAFP00000007481	ENSCAFP00000042345	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Terminal nucleotidyltransferase 4B.	0.475
DIS3	TUT7	ENSCAFP00000007481	ENSCAFP00000038915	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Terminal uridylyl transferase 7.	0.592
DIS3	XRN1	ENSCAFP00000007481	ENSCAFP00000051235	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	5'-3' exoribonuclease 1.	0.792
DIS3L2	LIN28A	ENSCAFP00000054971	ENSCAFP00000018394	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	Lin-28 homolog A.	0.553
DIS3L2	TDRKH	ENSCAFP00000054971	ENSCAFP00000018935	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	Tudor and KH domain containing.	0.407
DIS3L2	TUT7	ENSCAFP00000054971	ENSCAFP00000038915	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	Terminal uridylyl transferase 7.	0.858
DIS3L2	XRN1	ENSCAFP00000054971	ENSCAFP00000051235	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	5'-3' exoribonuclease 1.	0.584
LIN28A	DIS3L2	ENSCAFP00000018394	ENSCAFP00000054971	Lin-28 homolog A.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.553
LIN28A	TUT7	ENSCAFP00000018394	ENSCAFP00000038915	Lin-28 homolog A.	Terminal uridylyl transferase 7.	0.685
LIN28B	TUT7	ENSCAFP00000059700	ENSCAFP00000038915	Lin-28 homolog B.	Terminal uridylyl transferase 7.	0.546
PABPC1	AGO2	ENSCAFP00000039955	ENSCAFP00000043303	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.490
PABPC1	TUT7	ENSCAFP00000039955	ENSCAFP00000038915	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Terminal uridylyl transferase 7.	0.657
PABPC1	XRN1	ENSCAFP00000039955	ENSCAFP00000051235	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	5'-3' exoribonuclease 1.	0.505
PNLDC1	TDRKH	ENSCAFP00000001049	ENSCAFP00000018935	PARN like, ribonuclease domain containing 1.	Tudor and KH domain containing.	0.946
PNLDC1	TUT7	ENSCAFP00000001049	ENSCAFP00000038915	PARN like, ribonuclease domain containing 1.	Terminal uridylyl transferase 7.	0.544
PNLDC1	XRN1	ENSCAFP00000001049	ENSCAFP00000051235	PARN like, ribonuclease domain containing 1.	5'-3' exoribonuclease 1.	0.489
TDRKH	DIS3L2	ENSCAFP00000018935	ENSCAFP00000054971	Tudor and KH domain containing.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.407