GOLPH3L protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GOLPH3L

Golgi phosphoprotein 3 like. (285 aa)

Predicted Functional Partners:

SACM1L

0.832

HORMAD1

0.778

THOC5

0.682

EIF4E3

0.605

CDC5L

0.573

ZNF772

0.565

ZNF134

0.565

MAN2A1

0.563

SNRNP200

0.559

MYO18A

0.553

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC5L	EIF4E3	ENSCAFP00000002938	ENSCAFP00000041921	Cell division cycle 5 like.	Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.	0.438
CDC5L	GOLPH3L	ENSCAFP00000002938	ENSCAFP00000039007	Cell division cycle 5 like.	Golgi phosphoprotein 3 like.	0.573
CDC5L	SNRNP200	ENSCAFP00000002938	ENSCAFP00000065424	Cell division cycle 5 like.	Small nuclear ribonucleoprotein U5 subunit 200.	0.972
EIF4E3	CDC5L	ENSCAFP00000041921	ENSCAFP00000002938	Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.	Cell division cycle 5 like.	0.438
EIF4E3	GOLPH3L	ENSCAFP00000041921	ENSCAFP00000039007	Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.	Golgi phosphoprotein 3 like.	0.605
EIF4E3	HORMAD1	ENSCAFP00000041921	ENSCAFP00000017772	Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	0.412
GOLPH3L	CDC5L	ENSCAFP00000039007	ENSCAFP00000002938	Golgi phosphoprotein 3 like.	Cell division cycle 5 like.	0.573
GOLPH3L	EIF4E3	ENSCAFP00000039007	ENSCAFP00000041921	Golgi phosphoprotein 3 like.	Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.	0.605
GOLPH3L	HORMAD1	ENSCAFP00000039007	ENSCAFP00000017772	Golgi phosphoprotein 3 like.	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	0.778
GOLPH3L	MAN2A1	ENSCAFP00000039007	ENSCAFP00000011020	Golgi phosphoprotein 3 like.	Alpha-mannosidase.	0.563
GOLPH3L	MYO18A	ENSCAFP00000039007	ENSCAFP00000056918	Golgi phosphoprotein 3 like.	Myosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.553
GOLPH3L	SACM1L	ENSCAFP00000039007	ENSCAFP00000059561	Golgi phosphoprotein 3 like.	SAC1 like phosphatidylinositide phosphatase.	0.832
GOLPH3L	SNRNP200	ENSCAFP00000039007	ENSCAFP00000065424	Golgi phosphoprotein 3 like.	Small nuclear ribonucleoprotein U5 subunit 200.	0.559
GOLPH3L	THOC5	ENSCAFP00000039007	ENSCAFP00000018093	Golgi phosphoprotein 3 like.	THO complex 5.	0.682
GOLPH3L	ZNF134	ENSCAFP00000039007	ENSCAFP00000037488	Golgi phosphoprotein 3 like.	Zinc finger protein 134.	0.565
GOLPH3L	ZNF772	ENSCAFP00000039007	ENSCAFP00000036347	Golgi phosphoprotein 3 like.	Zinc finger protein 772.	0.565
HORMAD1	EIF4E3	ENSCAFP00000017772	ENSCAFP00000041921	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.	0.412
HORMAD1	GOLPH3L	ENSCAFP00000017772	ENSCAFP00000039007	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Golgi phosphoprotein 3 like.	0.778
HORMAD1	THOC5	ENSCAFP00000017772	ENSCAFP00000018093	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	THO complex 5.	0.461
HORMAD1	ZNF134	ENSCAFP00000017772	ENSCAFP00000037488	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Zinc finger protein 134.	0.485