STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (760 aa)    
Predicted Functional Partners:
GRM1
Glutamate metabotropic receptor 1.
   
 0.927
ZNFX1
Zinc finger NFX1-type containing 1.
   
  
 0.788
PPP1R9B
Protein phosphatase 1 regulatory subunit 9B.
    
 
 0.778
RRAGD
Ras related GTP binding D.
   
  
 0.691
LNX1
Ligand of numb-protein X 1.
    
 
 0.655
IQSEC2
IQ motif and Sec7 domain 2.
   
 
 0.651
BCAS4
Uncharacterized protein.
      
 0.645
NUFIP1
Nuclear FMR1 interacting protein 1.
   
  
 0.642
DLGAP1
DLG associated protein 1.
   
 
 0.627
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
    
 
 0.610
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.