Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM170BTransmembrane protein 170B. (202 aa)    
Predicted Functional Partners:
TMEM98
Transmembrane protein 98.
      
 0.792
TMEM45B
Transmembrane protein 45B.
      
 0.777
TMEM88
Transmembrane protein 88.
      
 0.687
TMEM168
Transmembrane protein 168.
   
  
 0.629
FRAT2
FRAT regulator of WNT signaling pathway 2.
      
 0.622
TMEM45A
Transmembrane protein 45A.
      
 0.610
CSNK1A1
Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily.
      
 0.591
VSTM4
V-set and transmembrane domain containing 4.
      
 0.519
CTNNA2
Catenin alpha 2.
   
  
 0.490
TMEM119
Transmembrane protein 119.
      
 0.462
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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