STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1343 aa)    
Predicted Functional Partners:
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
    
 0.961
MAPK10
Mitogen-activated protein kinase.
   
 0.942
MAPK8
Mitogen-activated protein kinase.
   
 0.942
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
 0.941
MAPK9
Mitogen-activated protein kinase.
   
 0.936
MAP3K11
Mitogen-activated protein kinase kinase kinase 11.
   
 0.919
L3MBTL2
L3MBTL histone methyl-lysine binding protein 2.
   
  
 0.809
NRXN2
Neurexin 2.
      
 0.733
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.724
NFKBIL1
NFKB inhibitor like 1.
      
 0.706
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.