STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9P193_CANLFNudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (176 aa)    
Predicted Functional Partners:
MEGF6
Multiple EGF like domains 6.
      
 0.501
GTF2E1
General transcription factor IIE subunit 1.
      
 0.483
GTF2F2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
      
 0.480
BMP3
Bone morphogenetic protein 3; Belongs to the TGF-beta family.
      
 0.457
FGF2
Spermatogenesis associated 5.
      
 0.457
PGAP2
Post-GPI attachment to proteins 2.
      
 0.454
DPP10
Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.
      
 0.407
SLC17A5
Solute carrier family 17 member 5.
      
 0.407
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.