STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL10A1Collagen type X alpha 1 chain. (677 aa)    
Predicted Functional Partners:
ACAN
Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
   
 
 0.828
MMP13
Matrix metallopeptidase 13.
   
 
 0.800
RUNX2
RUNX family transcription factor 2.
      
 0.764
ALPL
Alkaline phosphatase.
   
  
 0.721
COL2A1
Collagen type II alpha 1 chain.
  
0.715
COMP
Cartilage oligomeric matrix protein.
   
 
 0.680
ENSCAFP00000064001
Endostatin domain-containing protein.
 
  
   0.659
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5.
    
 
 0.638
P4HB
Protein disulfide-isomerase.
   
 0.622
COL9A1
Collagen type IX alpha 1 chain.
  
 
0.617
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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