STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIK5Uncharacterized protein. (981 aa)    
Predicted Functional Partners:
IGSF23
Immunoglobulin superfamily member 23.
      
 0.843
GRIK3
Glutamate ionotropic receptor kainate type subunit 3.
  
 
0.812
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
  
 
0.798
GRIK1
Glutamate ionotropic receptor kainate type subunit 1.
  
 
0.798
KCNC1
Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family.
   
  
 0.767
ANO8
Anoctamin.
   
  
 0.733
KCNG1
Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family.
   
  
 0.714
PANX2
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.707
GRM2
Glutamate metabotropic receptor 2.
   
  
 0.683
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
   
  
 0.646
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.