STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR22G protein-coupled receptor 22. (433 aa)    
Predicted Functional Partners:
DUS4L
tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.
      
 0.874
COG5
Component of oligomeric golgi complex 5.
      
 0.818
PRKAR2B
Protein kinase cAMP-dependent type II regulatory subunit beta.
    
 
 0.733
GPR142
G-protein coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.
      
 0.680
GPR171
G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family.
      
 0.677
PTH2R
Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.
      
 0.676
SCTR
Secretin receptor; Belongs to the G-protein coupled receptor 2 family.
      
 0.661
P2RY10
P2Y receptor family member 10.
      
 0.635
PTGER1
Prostaglandin E2 receptor EP1 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues (By similarity). Belongs to the G-protein coupled receptor 1 family.
      
 0.614
GRPR
Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.540
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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