STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTX1Orthodenticle homeobox 1. (355 aa)    
Predicted Functional Partners:
WDR70
WD repeat domain 70.
      
 0.689
TBR1
T-box brain transcription factor 1.
   
 
 0.677
TGM7
Transglutaminase 7.
      
 0.643
NANOGNB
Homeobox domain-containing protein.
      
 0.594
OXSR1
Oxidative stress responsive kinase 1.
      
 0.562
LHFPL5
LHFPL tetraspan subfamily member 5.
   
  
 0.543
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
    
 
 0.493
SATB2
DNA-binding protein SATB.
      
 0.485
GDF3
Growth differentiation factor 3.
   
  
 0.484
LRRCC1
Leucine rich repeat and coiled-coil centrosomal protein 1.
      
 0.483
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.