STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (393 aa)    
Predicted Functional Partners:
SYVN1
Synoviolin 1.
   
 
 0.814
COA7
Cytochrome c oxidase assembly factor 7 (putative).
   
 
 0.703
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
  
 0.696
XBP1
BZIP domain-containing protein.
   
  
 0.666
EDEM1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.652
SDF2L1
Stromal cell derived factor 2 like 1.
   
  
 0.646
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
  
 0.645
RIMKLB
Ribosomal modification protein rimK like family member B.
      
 0.642
MANF
Mesencephalic astrocyte derived neurotrophic factor.
      
 0.636
AMFR
Autocrine motility factor receptor.
   
 
 0.632
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.