STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRMSpermidine synthase; Belongs to the spermidine/spermine synthase family. (351 aa)    
Predicted Functional Partners:
AMD1
Adenosylmethionine decarboxylase 1.
    
 0.994
AGMAT
Agmatinase; Belongs to the arginase family.
  
 
 0.988
ODC1
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.988
SMS
Spermine synthase.
  
  
 0.983
MTAP
Methylthioadenosine phosphorylase.
  
 
 0.975
SMOX
Spermine oxidase.
     
 0.969
SAT2
Spermidine/spermine N1-acetyltransferase family member 2.
     
 0.945
AOC1
Amine oxidase.
     
 0.943
SAT1
Spermidine/spermine N1-acetyltransferase 1.
     
 0.943
AASS
Aminoadipate-semialdehyde synthase.
    
 0.925
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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