STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9P2Y8_CANLFUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (233 aa)    
Predicted Functional Partners:
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 
 0.662
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.633
BBS7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 
 0.613
ITSN2
Intersectin 2.
    
 
 0.603
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 
 0.597
BBS1
BBS1 domain-containing protein.
   
 
 0.587
LOC100856635
Uncharacterized protein.
    
 
 0.568
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.568
ITSN1
Intersectin 1.
    
 
 0.568
TTC8
Tetratricopeptide repeat domain 8 isoform 1.
   
 
 0.539
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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