STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9P328_CANLFWH1 domain-containing protein. (137 aa)    
Predicted Functional Partners:
EVL
Enah/Vasp-like.
    
 
0.893
ENAH
ENAH actin regulator.
    
 
0.857
PFN2
Profilin; Belongs to the profilin family.
   
 
 0.755
ZYX
Zyxin.
   
 
 0.746
PFN4
Profilin; Belongs to the profilin family.
   
 
 0.738
VCL
Vinculin.
    
 
 0.721
LOC106558389
Profilin; Belongs to the profilin family.
   
 
 0.686
ABI1
Abl interactor 1.
    
 
 0.660
TES
Testin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity); Belongs to the prickle / espinas / testin family.
   
 
 0.625
PFN1
Profilin; Belongs to the profilin family.
   
 
 0.616
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (12%) [HD]