STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK1Tyrosine-protein kinase. (1154 aa)    
Predicted Functional Partners:
STAT1
Signal transducer and activator of transcription.
   
 0.998
TYK2
Tyrosine-protein kinase.
  
0.995
STAT3
Signal transducer and activator of transcription.
   
 0.995
LOC609830
Uncharacterized protein.
   
 0.994
IL10RA
Interleukin 10 receptor subunit alpha.
   
 0.994
IFNAR1
Uncharacterized protein.
   
 0.994
IFNLR1
Interferon lambda receptor 1.
    
 0.992
STAT2
Signal transducer and activator of transcription.
   
 0.991
STAT4
Signal transducer and activator of transcription.
   
 0.987
IFNAR2
Uncharacterized protein.
   
 0.987
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.