node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTNL9 | FAF2 | ENSCAFP00000019022 | ENSCAFP00000024535 | Butyrophilin like 9. | Fas associated factor family member 2. | 0.651 |
BTNL9 | LMAN2 | ENSCAFP00000019022 | ENSCAFP00000024181 | Butyrophilin like 9. | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | 0.643 |
DERL2 | FAF2 | ENSCAFP00000055568 | ENSCAFP00000024535 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Fas associated factor family member 2. | 0.814 |
DERL2 | LMAN2 | ENSCAFP00000055568 | ENSCAFP00000024181 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | 0.718 |
DERL2 | MOGS | ENSCAFP00000055568 | ENSCAFP00000012442 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Mannosyl-oligosaccharide glucosidase. | 0.639 |
DERL2 | POLR3F | ENSCAFP00000055568 | ENSCAFP00000008061 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.537 |
DERL2 | SEL1L | ENSCAFP00000055568 | ENSCAFP00000056064 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.988 |
DERL2 | UBE2J1 | ENSCAFP00000055568 | ENSCAFP00000004615 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Ubiquitin conjugating enzyme E2 J1. | 0.709 |
DERL2 | UBE2J2 | ENSCAFP00000055568 | ENSCAFP00000038414 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Ubiquitin conjugating enzyme E2 J2. | 0.719 |
FAF2 | BTNL9 | ENSCAFP00000024535 | ENSCAFP00000019022 | Fas associated factor family member 2. | Butyrophilin like 9. | 0.651 |
FAF2 | DERL2 | ENSCAFP00000024535 | ENSCAFP00000055568 | Fas associated factor family member 2. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.814 |
FAF2 | LMAN2 | ENSCAFP00000024535 | ENSCAFP00000024181 | Fas associated factor family member 2. | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | 0.656 |
FAF2 | SEL1L | ENSCAFP00000024535 | ENSCAFP00000056064 | Fas associated factor family member 2. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.781 |
FAF2 | UBE2J1 | ENSCAFP00000024535 | ENSCAFP00000004615 | Fas associated factor family member 2. | Ubiquitin conjugating enzyme E2 J1. | 0.451 |
FAF2 | UBE2J2 | ENSCAFP00000024535 | ENSCAFP00000038414 | Fas associated factor family member 2. | Ubiquitin conjugating enzyme E2 J2. | 0.458 |
LMAN2 | BTNL9 | ENSCAFP00000024181 | ENSCAFP00000019022 | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | Butyrophilin like 9. | 0.643 |
LMAN2 | DERL2 | ENSCAFP00000024181 | ENSCAFP00000055568 | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.718 |
LMAN2 | FAF2 | ENSCAFP00000024181 | ENSCAFP00000024535 | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | Fas associated factor family member 2. | 0.656 |
LMAN2 | MOGS | ENSCAFP00000024181 | ENSCAFP00000012442 | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | Mannosyl-oligosaccharide glucosidase. | 0.762 |
LMAN2 | POLR3F | ENSCAFP00000024181 | ENSCAFP00000008061 | Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.712 |