STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB5Integrin beta; Belongs to the integrin beta chain family. (810 aa)    
Predicted Functional Partners:
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.996
PAK4
Non-specific serine/threonine protein kinase.
   
 
 0.988
TLN1
Talin 1.
   
 0.941
PELO
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 0.939
PXN
Paxillin.
   
 0.918
VCL
Vinculin.
   
 0.918
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
   
 0.880
VTN
SMB domain-containing protein.
   
 0.851
ITGA2
Integrin subunit alpha 2; Belongs to the integrin alpha chain family.
   
 0.846
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 
 0.818
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.