STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1268 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.964
EXO1
Exonuclease 1.
   
 
 0.862
DTL
Denticleless E3 ubiquitin protein ligase homolog.
   
 
 0.860
CDC20
Cell division cycle 20.
   
 0.860
NUDC
Nuclear distribution C, dynein complex regulator.
   
 
  0.802
CENPI
Centromere protein I.
   
 
 0.800
PTPDC1
Protein tyrosine phosphatase domain containing 1.
   
  
 0.787
CCDC73
Coiled-coil domain containing 73.
   
  
 0.769
AUNIP
Aurora kinase A and ninein interacting protein.
   
  
 0.764
SKA3
Spindle and kinetochore associated complex subunit 3.
   
 
 0.745
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.