STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPHX3Epoxide hydrolase 3. (279 aa)    
Predicted Functional Partners:
EPHX1
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
   
  
 0.792
ILVBL
IlvB acetolactate synthase like; Belongs to the TPP enzyme family.
     
 0.708
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.671
FOXRED2
FAD dependent oxidoreductase domain containing 2.
   
 0.575
SYDE1
Synapse defective Rho GTPase homolog 1.
      
 0.563
CRYZ
PKS_ER domain-containing protein.
  
 0.556
CYP2W1
Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family.
   
 
 0.542
RAB44
RAB44, member RAS oncogene family.
   
  
 0.541
PTX4
Pentraxin 4.
      
 0.523
SBSN
Uncharacterized protein.
   
 
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.