STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LONRF1LON peptidase N-terminal domain and ring finger 1. (737 aa)    
Predicted Functional Partners:
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
      
 0.703
C16H8orf48
Chromosome 16 C8orf48 homolog.
      
 0.660
LSM1
U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.
      
 0.563
PGM2
Phosphoglucomutase 2.
   
  
 0.538
DOC2B
Double C2-like domain-containing protein.
   
  
 0.527
SERTAD1
SERTA domain containing 1.
      
 0.515
BDH2
Uncharacterized protein.
      
 0.514
CAMK1D
Calcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily.
      
 0.514
CDK17
Cyclin dependent kinase 17.
      
 0.510
DDB2
Damage specific DNA binding protein 2.
   
  
 0.510
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.