Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC42-2 | GSK3B | ENSCAFP00000060180 | ENSCAFP00000034412 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.469 |
| CDC42-2 | MPP5 | ENSCAFP00000060180 | ENSCAFP00000024081 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells. Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface. Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required for the maintenance of cerebell [...] | 0.499 |
| CDC42-2 | PARD3 | ENSCAFP00000060180 | ENSCAFP00000005582 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-3 family cell polarity regulator. | 0.940 |
| CDC42-2 | PARD6A | ENSCAFP00000060180 | ENSCAFP00000040187 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-6 family cell polarity regulator alpha. | 0.973 |
| CDC42-2 | PRKCI | ENSCAFP00000060180 | ENSCAFP00000021856 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.927 |
| CDC42-2 | PRKCZ | ENSCAFP00000060180 | ENSCAFP00000028644 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.938 |
| CDC42-2 | RAC2 | ENSCAFP00000060180 | ENSCAFP00000002174 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 2. | 0.919 |
| CDC42-2 | RAC3 | ENSCAFP00000060180 | ENSCAFP00000008868 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.925 |
| CRB3 | MPP5 | ENSCAFP00000044539 | ENSCAFP00000024081 | Crumbs cell polarity complex component 3. | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells. Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface. Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required for the maintenance of cerebell [...] | 0.995 |
| CRB3 | PARD3 | ENSCAFP00000044539 | ENSCAFP00000005582 | Crumbs cell polarity complex component 3. | Par-3 family cell polarity regulator. | 0.482 |
| CRB3 | PARD6A | ENSCAFP00000044539 | ENSCAFP00000040187 | Crumbs cell polarity complex component 3. | Par-6 family cell polarity regulator alpha. | 0.917 |
| CRB3 | PRKCI | ENSCAFP00000044539 | ENSCAFP00000021856 | Crumbs cell polarity complex component 3. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.515 |
| DVL2 | GSK3B | ENSCAFP00000023701 | ENSCAFP00000034412 | Dishevelled segment polarity protein 2. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.958 |
| DVL2 | PARD6A | ENSCAFP00000023701 | ENSCAFP00000040187 | Dishevelled segment polarity protein 2. | Par-6 family cell polarity regulator alpha. | 0.913 |
| DVL2 | RAC2 | ENSCAFP00000023701 | ENSCAFP00000002174 | Dishevelled segment polarity protein 2. | Rac family small GTPase 2. | 0.540 |
| GSK3B | CDC42-2 | ENSCAFP00000034412 | ENSCAFP00000060180 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.469 |
| GSK3B | DVL2 | ENSCAFP00000034412 | ENSCAFP00000023701 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Dishevelled segment polarity protein 2. | 0.958 |
| GSK3B | PARD3 | ENSCAFP00000034412 | ENSCAFP00000005582 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Par-3 family cell polarity regulator. | 0.912 |
| GSK3B | PARD6A | ENSCAFP00000034412 | ENSCAFP00000040187 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Par-6 family cell polarity regulator alpha. | 0.915 |
| GSK3B | PRKCZ | ENSCAFP00000034412 | ENSCAFP00000028644 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.910 |
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