STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM15PR/SET domain 15. (1175 aa)    
Predicted Functional Partners:
CDCP2
CUB domain containing protein 2.
      
 0.660
PLBD1
Phospholipase B-like; Putative phospholipase.
      
 0.647
COPZ2
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
      
 0.647
OTUD7A
OTU deubiquitinase 7A.
   
  
 0.645
EFEMP2
EGF containing fibulin extracellular matrix protein 2.
   
 
 0.600
FBXL21
F-box domain-containing protein.
   
 
 0.598
CCDC66
Coiled-coil domain-containing protein 66; Microtubule-binding protein required for ciliogenesis. May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites (By similarity). Plays a role in retina morphogenesis and/or homeostasis.
      
 0.592
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
      
 0.591
TMEM109
Transmembrane protein 132A.
      
 0.568
PRUNE2
Prune homolog 2 with BCH domain.
      
 0.564
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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