STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX43DEAD-box helicase 43; Belongs to the DEAD box helicase family. (645 aa)    
Predicted Functional Partners:
OOEP
Oocyte-expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions; Belongs to the KHDC1 family.
   
  
 0.815
DPPA5
Developmental pluripotency associated 5.
   
  
 0.717
DUSP21
Dual specificity phosphatase 21; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 
 0.648
KCNQ5
Potassium voltage-gated channel subfamily Q member 5.
 
 
 
 0.633
RIMS1
Regulating synaptic membrane exocytosis 1.
   
  
 0.626
APMAP
Adipocyte plasma membrane associated protein.
  
 
 0.534
PNPT1
Polyribonucleotide nucleotidyltransferase 1.
  
 
 0.531
ENSCAFP00000055070
Uncharacterized protein.
  
     0.528
MAGEB10
Melanoma-associated antigen B10.
   
 
 0.524
DDX60
DExD/H-box helicase 60.
   
 
 0.522
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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