LOC488289 protein (Canis lupus familiaris) - STRING interaction network

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Score

LOC488289

Histone H2A; Belongs to the histone H2A family. (130 aa)

Predicted Functional Partners:

KDM1A

0.871

LOC488290

0.862

RCOR1

0.836

LOC111090006

0.805

LOC488303

0.779

MYSM1

0.762

LOC478743

0.732

H2BC21

0.732

KDM6B

0.722

LOC612779

0.716

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2BC21	KDM1A	ENSCAFP00000038958	ENSCAFP00000053375	Histone H2B; Belongs to the histone H2B family.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.671
H2BC21	KDM6B	ENSCAFP00000038958	ENSCAFP00000061587	Histone H2B; Belongs to the histone H2B family.	Lysine demethylase 6B.	0.718
H2BC21	LOC111090006	ENSCAFP00000038958	ENSCAFP00000041760	Histone H2B; Belongs to the histone H2B family.	Histone H3; Belongs to the histone H3 family.	0.792
H2BC21	LOC478743	ENSCAFP00000038958	ENSCAFP00000036635	Histone H2B; Belongs to the histone H2B family.	Histone H2B; Belongs to the histone H2B family.	0.404
H2BC21	LOC488289	ENSCAFP00000038958	ENSCAFP00000040788	Histone H2B; Belongs to the histone H2B family.	Histone H2A; Belongs to the histone H2A family.	0.732
H2BC21	LOC488290	ENSCAFP00000038958	ENSCAFP00000041361	Histone H2B; Belongs to the histone H2B family.	Histone H2B; Belongs to the histone H2B family.	0.707
H2BC21	LOC488303	ENSCAFP00000038958	ENSCAFP00000045708	Histone H2B; Belongs to the histone H2B family.	Histone H2B type 1-K.	0.532
H2BC21	LOC612779	ENSCAFP00000038958	ENSCAFP00000040000	Histone H2B; Belongs to the histone H2B family.	Histone H3; Belongs to the histone H3 family.	0.745
H2BC21	RCOR1	ENSCAFP00000038958	ENSCAFP00000026701	Histone H2B; Belongs to the histone H2B family.	REST corepressor 1.	0.602
KDM1A	H2BC21	ENSCAFP00000053375	ENSCAFP00000038958	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone H2B; Belongs to the histone H2B family.	0.671
KDM1A	KDM6B	ENSCAFP00000053375	ENSCAFP00000061587	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Lysine demethylase 6B.	0.453
KDM1A	LOC111090006	ENSCAFP00000053375	ENSCAFP00000041760	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone H3; Belongs to the histone H3 family.	0.899
KDM1A	LOC478743	ENSCAFP00000053375	ENSCAFP00000036635	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone H2B; Belongs to the histone H2B family.	0.671
KDM1A	LOC488289	ENSCAFP00000053375	ENSCAFP00000040788	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone H2A; Belongs to the histone H2A family.	0.871
KDM1A	LOC488290	ENSCAFP00000053375	ENSCAFP00000041361	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone H2B; Belongs to the histone H2B family.	0.801
KDM1A	LOC488303	ENSCAFP00000053375	ENSCAFP00000045708	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone H2B type 1-K.	0.620
KDM1A	LOC612779	ENSCAFP00000053375	ENSCAFP00000040000	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone H3; Belongs to the histone H3 family.	0.914
KDM1A	RCOR1	ENSCAFP00000053375	ENSCAFP00000026701	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	REST corepressor 1.	0.998
KDM6B	H2BC21	ENSCAFP00000061587	ENSCAFP00000038958	Lysine demethylase 6B.	Histone H2B; Belongs to the histone H2B family.	0.718
KDM6B	KDM1A	ENSCAFP00000061587	ENSCAFP00000053375	Lysine demethylase 6B.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.453