STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC19DnaJ heat shock protein family (Hsp40) member C19. (116 aa)    
Predicted Functional Partners:
TTC14
Tetratricopeptide repeat domain 14.
   
  
 0.896
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
      
 0.793
PHB2
Prohibitin.
    
 
 0.708
HSPA9
Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family.
   
 
 0.690
CLDN18
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.650
TIMM17A
Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
   
 
 0.638
FXR1
FMR1 autosomal homolog 1.
   
  
 0.638
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
   
 
 0.624
J9P0Q7_CANLF
Prohibitin.
    
 
 0.612
J9P9X2_CANLF
Prohibitin.
    
 
 0.612
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.