LOC102156989 protein (Canis lupus familiaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC102156989

N-terminal Ras-GEF domain-containing protein. (626 aa)

Predicted Functional Partners:

RALB

0.722

KRAS

0.657

RALA

0.647

MRAS

0.632

RAP1B

0.616

RRAS

0.615

RAP1A

0.493

REM1

0.479

RIN1

0.469

TBXA2R

0.452

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRAS	LOC102156989	ENSCAFP00000064230	ENSCAFP00000040987	KRAS proto-oncogene, GTPase.	N-terminal Ras-GEF domain-containing protein.	0.657
KRAS	RAP1A	ENSCAFP00000064230	ENSCAFP00000040927	KRAS proto-oncogene, GTPase.	RAP1A, member of RAS oncogene family.	0.530
KRAS	RAP1B	ENSCAFP00000064230	ENSCAFP00000000596	KRAS proto-oncogene, GTPase.	RAP1B, member of RAS oncogene family.	0.531
LOC102156989	KRAS	ENSCAFP00000040987	ENSCAFP00000064230	N-terminal Ras-GEF domain-containing protein.	KRAS proto-oncogene, GTPase.	0.657
LOC102156989	MRAS	ENSCAFP00000040987	ENSCAFP00000011185	N-terminal Ras-GEF domain-containing protein.	Muscle RAS oncogene homolog.	0.632
LOC102156989	RALA	ENSCAFP00000040987	ENSCAFP00000037840	N-terminal Ras-GEF domain-containing protein.	RAS like proto-oncogene A.	0.647
LOC102156989	RALB	ENSCAFP00000040987	ENSCAFP00000007237	N-terminal Ras-GEF domain-containing protein.	RAS like proto-oncogene B.	0.722
LOC102156989	RAP1A	ENSCAFP00000040987	ENSCAFP00000040927	N-terminal Ras-GEF domain-containing protein.	RAP1A, member of RAS oncogene family.	0.493
LOC102156989	RAP1B	ENSCAFP00000040987	ENSCAFP00000000596	N-terminal Ras-GEF domain-containing protein.	RAP1B, member of RAS oncogene family.	0.616
LOC102156989	REM1	ENSCAFP00000040987	ENSCAFP00000037790	N-terminal Ras-GEF domain-containing protein.	RRAD and GEM like GTPase 1.	0.479
LOC102156989	RIN1	ENSCAFP00000040987	ENSCAFP00000018837	N-terminal Ras-GEF domain-containing protein.	Ras and Rab interactor 1.	0.469
LOC102156989	RRAS	ENSCAFP00000040987	ENSCAFP00000044955	N-terminal Ras-GEF domain-containing protein.	RAS related.	0.615
LOC102156989	TBXA2R	ENSCAFP00000040987	ENSCAFP00000028282	N-terminal Ras-GEF domain-containing protein.	Thromboxane A2 receptor.	0.452
MRAS	LOC102156989	ENSCAFP00000011185	ENSCAFP00000040987	Muscle RAS oncogene homolog.	N-terminal Ras-GEF domain-containing protein.	0.632
MRAS	RIN1	ENSCAFP00000011185	ENSCAFP00000018837	Muscle RAS oncogene homolog.	Ras and Rab interactor 1.	0.924
RALA	LOC102156989	ENSCAFP00000037840	ENSCAFP00000040987	RAS like proto-oncogene A.	N-terminal Ras-GEF domain-containing protein.	0.647
RALA	RALB	ENSCAFP00000037840	ENSCAFP00000007237	RAS like proto-oncogene A.	RAS like proto-oncogene B.	0.922
RALB	LOC102156989	ENSCAFP00000007237	ENSCAFP00000040987	RAS like proto-oncogene B.	N-terminal Ras-GEF domain-containing protein.	0.722
RALB	RALA	ENSCAFP00000007237	ENSCAFP00000037840	RAS like proto-oncogene B.	RAS like proto-oncogene A.	0.922
RAP1A	KRAS	ENSCAFP00000040927	ENSCAFP00000064230	RAP1A, member of RAS oncogene family.	KRAS proto-oncogene, GTPase.	0.530