node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCB6 | ATG9A | ENSCAFP00000022311 | ENSCAFP00000055642 | ATP binding cassette subfamily B member 6. | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | 0.519 |
ABCB6 | DLC1 | ENSCAFP00000022311 | ENSCAFP00000010111 | ATP binding cassette subfamily B member 6. | Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity). | 0.440 |
ABCB6 | HS1BP3 | ENSCAFP00000022311 | ENSCAFP00000041026 | ATP binding cassette subfamily B member 6. | HCLS1 binding protein 3. | 0.606 |
ATG9A | ABCB6 | ENSCAFP00000055642 | ENSCAFP00000022311 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | ATP binding cassette subfamily B member 6. | 0.519 |
ATG9A | DLC1 | ENSCAFP00000055642 | ENSCAFP00000010111 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity). | 0.560 |
ATG9A | HS1BP3 | ENSCAFP00000055642 | ENSCAFP00000041026 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | HCLS1 binding protein 3. | 0.750 |
BAG6 | HS1BP3 | ENSCAFP00000000828 | ENSCAFP00000041026 | BCL2 associated athanogene 6. | HCLS1 binding protein 3. | 0.515 |
BAG6 | THEMIS2 | ENSCAFP00000000828 | ENSCAFP00000017659 | BCL2 associated athanogene 6. | Thymocyte selection associated family member 2. | 0.480 |
CTNS | HS1BP3 | ENSCAFP00000060649 | ENSCAFP00000041026 | Cystinosin, lysosomal cystine transporter. | HCLS1 binding protein 3. | 0.499 |
DLC1 | ABCB6 | ENSCAFP00000010111 | ENSCAFP00000022311 | Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity). | ATP binding cassette subfamily B member 6. | 0.440 |
DLC1 | ATG9A | ENSCAFP00000010111 | ENSCAFP00000055642 | Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity). | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | 0.560 |
DLC1 | HS1BP3 | ENSCAFP00000010111 | ENSCAFP00000041026 | Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity). | HCLS1 binding protein 3. | 0.707 |
ENSCAFP00000053367 | HS1BP3 | ENSCAFP00000053367 | ENSCAFP00000041026 | Uncharacterized protein. | HCLS1 binding protein 3. | 0.483 |
HS1BP3 | ABCB6 | ENSCAFP00000041026 | ENSCAFP00000022311 | HCLS1 binding protein 3. | ATP binding cassette subfamily B member 6. | 0.606 |
HS1BP3 | ATG9A | ENSCAFP00000041026 | ENSCAFP00000055642 | HCLS1 binding protein 3. | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | 0.750 |
HS1BP3 | BAG6 | ENSCAFP00000041026 | ENSCAFP00000000828 | HCLS1 binding protein 3. | BCL2 associated athanogene 6. | 0.515 |
HS1BP3 | CTNS | ENSCAFP00000041026 | ENSCAFP00000060649 | HCLS1 binding protein 3. | Cystinosin, lysosomal cystine transporter. | 0.499 |
HS1BP3 | DLC1 | ENSCAFP00000041026 | ENSCAFP00000010111 | HCLS1 binding protein 3. | Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity). | 0.707 |
HS1BP3 | ENSCAFP00000053367 | ENSCAFP00000041026 | ENSCAFP00000053367 | HCLS1 binding protein 3. | Uncharacterized protein. | 0.483 |
HS1BP3 | NIPSNAP1 | ENSCAFP00000041026 | ENSCAFP00000018104 | HCLS1 binding protein 3. | Nipsnap homolog 1. | 0.466 |