STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGLYRP2Peptidoglycan recognition protein 2. (499 aa)    
Predicted Functional Partners:
MGAM2
Maltase-glucoamylase 2 (putative).
   
 
 0.861
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
   
 
 0.828
PIGS
Phosphatidylinositol glycan anchor biosynthesis class S.
   
 
 0.821
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 
 0.817
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
   
 
 0.791
MGAM
Maltase-glucoamylase.
   
 
 0.679
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
      
 0.678
SPP1
Secreted phosphoprotein 1.
      
 0.573
VIM
IF rod domain-containing protein; Belongs to the intermediate filament family.
      
 0.438
FTCD
Formimidoyltransferase cyclodeaminase.
   
    0.427
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.