STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (239 aa)    
Predicted Functional Partners:
TRAK2
Trafficking kinesin protein 2.
   
  
 0.698
CLIC4
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
  
 
0.599
GLRA3
Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.561
GLRA2
Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.561
CACNB3
Calcium voltage-gated channel auxiliary subunit beta 3.
      
 0.555
CLIC5
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
  
 
0.544
IGSF3
Immunoglobulin superfamily member 3.
      
 0.523
FAM229B
Family with sequence similarity 229 member B.
      
 0.520
MAGEE2
MAGE family member E2.
      
 0.515
TTC39B
Tetratricopeptide repeat domain 39B.
      
 0.499
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.