STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRAS1Fraser extracellular matrix complex subunit 1. (4011 aa)    
Predicted Functional Partners:
FREM1
FRAS1 related extracellular matrix 1.
   
0.944
FREM2
FRAS1 related extracellular matrix 2.
   
0.933
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 
 0.928
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.904
NPNT
Nephronectin.
     
 0.820
SPATA25
Spermatogenesis associated 25.
      
 0.739
NEURL2
Neuralized E3 ubiquitin protein ligase 2.
      
 0.719
PHIP
Pleckstrin homology domain interacting protein.
      
 0.716
FAM163A
Family with sequence similarity 163 member A.
      
 0.698
LIMCH1
LIM and calponin homology domains 1.
   
  
 0.681
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.