PHRF1 protein (Canis lupus familiaris) - STRING interaction network

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Score

PHRF1

PHD and ring finger domains 1. (1626 aa)

Predicted Functional Partners:

APIP

0.878

SPPL3

0.853

TAOK3

0.837

DDX6

0.757

SH2B3

0.714

GTF3C1

0.660

ZNRD2

0.659

SIPA1

0.636

TRNT1

0.636

LSM10

0.606

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APIP	DDX6	ENSCAFP00000043546	ENSCAFP00000018313	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.739
APIP	PHRF1	ENSCAFP00000043546	ENSCAFP00000041446	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	PHD and ring finger domains 1.	0.878
APIP	SH2B3	ENSCAFP00000043546	ENSCAFP00000012613	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	SH2B adaptor protein 3.	0.719
APIP	SIPA1	ENSCAFP00000043546	ENSCAFP00000019684	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	Signal-induced proliferation-associated 1.	0.573
APIP	SPPL3	ENSCAFP00000043546	ENSCAFP00000042076	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	Signal peptide peptidase like 3.	0.856
APIP	TAOK3	ENSCAFP00000043546	ENSCAFP00000014624	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	TAO kinase 3.	0.824
APIP	ZNRD2	ENSCAFP00000043546	ENSCAFP00000056910	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	Zinc ribbon domain containing 2.	0.652
DDX6	APIP	ENSCAFP00000018313	ENSCAFP00000043546	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	0.739
DDX6	PHRF1	ENSCAFP00000018313	ENSCAFP00000041446	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	PHD and ring finger domains 1.	0.757
DDX6	SH2B3	ENSCAFP00000018313	ENSCAFP00000012613	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	SH2B adaptor protein 3.	0.474
DDX6	SPPL3	ENSCAFP00000018313	ENSCAFP00000042076	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Signal peptide peptidase like 3.	0.573
DDX6	TAOK3	ENSCAFP00000018313	ENSCAFP00000014624	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	TAO kinase 3.	0.603
GTF3C1	PHRF1	ENSCAFP00000025663	ENSCAFP00000041446	General transcription factor IIIC subunit 1.	PHD and ring finger domains 1.	0.660
LSM10	PHRF1	ENSCAFP00000005023	ENSCAFP00000041446	LSM10, U7 small nuclear RNA associated.	PHD and ring finger domains 1.	0.606
LSM10	TRNT1	ENSCAFP00000005023	ENSCAFP00000052670	LSM10, U7 small nuclear RNA associated.	tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	0.663
PHRF1	APIP	ENSCAFP00000041446	ENSCAFP00000043546	PHD and ring finger domains 1.	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	0.878
PHRF1	DDX6	ENSCAFP00000041446	ENSCAFP00000018313	PHD and ring finger domains 1.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.757
PHRF1	GTF3C1	ENSCAFP00000041446	ENSCAFP00000025663	PHD and ring finger domains 1.	General transcription factor IIIC subunit 1.	0.660
PHRF1	LSM10	ENSCAFP00000041446	ENSCAFP00000005023	PHD and ring finger domains 1.	LSM10, U7 small nuclear RNA associated.	0.606
PHRF1	SH2B3	ENSCAFP00000041446	ENSCAFP00000012613	PHD and ring finger domains 1.	SH2B adaptor protein 3.	0.714