STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPFIA3-2Uncharacterized protein. (243 aa)    
Predicted Functional Partners:
PPFIA3
PTPRF interacting protein alpha 3.
 
     0.937
PTPRD
Protein tyrosine phosphatase receptor type D.
    
 
 0.691
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 
 0.568
PPFIBP2
PPFIA binding protein 2.
   
 
0.555
PPFIBP1
PPFIA binding protein 1.
   
 
0.555
PPP2CB
Serine/threonine-protein phosphatase.
   
   0.550
PPP2CA
Serine/threonine-protein phosphatase.
   
   0.550
PTPRS
Protein tyrosine phosphatase receptor type S.
    
 
 0.542
PTPRF
Protein tyrosine phosphatase receptor type F.
    
 
 0.542
GIT2
GIT ArfGAP 2.
    
 
 0.530
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.