STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF212Ring finger protein 212. (318 aa)    
Predicted Functional Partners:
TEX11
Testis expressed 11.
    
 
 0.906
REC8
REC8 meiotic recombination protein.
    
 
 0.885
MSH4
MutS homolog 4.
   
 
 0.876
MLH3
MutL homolog 3.
      
 0.827
SHOC1
Shortage in chiasmata 1.
      
 0.824
IQCA1L
IQ motif containing with AAA domain 1 like.
    
 
 0.783
RAE1
SPO11 initiator of meiotic double stranded breaks.
   
 
 0.690
REC114
REC114 meiotic recombination protein.
    
 
 0.689
FAM189A1
Family with sequence similarity 189 member A1.
      
 0.675
HFM1
Helicase for meiosis 1.
      
 0.665
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.