STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1294 aa)    
Predicted Functional Partners:
ATF7IP
Activating transcription factor 7 interacting protein.
   
 0.992
ARL14EP
ADP ribosylation factor like GTPase 14 effector protein.
    
 
 0.973
DNMT3A
DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 
 0.829
LOC111090006
Histone H3; Belongs to the histone H3 family.
   
 0.802
LOC488263
Histone H3; Belongs to the histone H3 family.
   
 0.802
ATF7IP2
Activating transcription factor 7 interacting protein 2.
   
 
 0.734
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.707
SUV39H1
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
    
 
0.698
LOC480110
Histone H3; Belongs to the histone H3 family.
   
 
 0.683
LOC612779
Histone H3; Belongs to the histone H3 family.
   
 
 0.683
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.