STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPH3ARabphilin 3A. (699 aa)    
Predicted Functional Partners:
RAB3A
RAB3A, member RAS oncogene family.
   
 
 0.863
COL13A1
Collagen type XIII alpha 1 chain.
   
  
 0.807
EXPH5
Exophilin 5.
   
  
 0.784
COL25A1
Collagen type XXV alpha 1 chain.
   
  
 0.740
RAB27A
Ras-related protein Rab-27A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
    
 
 0.689
RAB3B
RAB3B, member RAS oncogene family.
   
 
 0.688
RIMS4
Regulating synaptic membrane exocytosis 4.
   
  
 0.650
RAB27B
RAB27B, member RAS oncogene family.
    
 
 0.637
SNAP25
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 
 0.583
OVCH2
Ovochymase 2; Belongs to the peptidase S1 family.
   
  
 0.577
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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